Dean of the College Presents
The Landscape of Notch Signaling and the Regulation of Germline Stem Cells in vivo
Thursday, December 10, 2015
Reem-Kayden Center Laszlo Z. Bito '60 Auditorium
12:00 pm EST/GMT-5
12:00 pm EST/GMT-5
Erika Sorensen-Kamakian
University of Wisconsin-Madison
University of Wisconsin-Madison
Notch signaling is an evolutionarily conserved signaling pathway critical during animal development and during adult tissue maintenance. Notch signaling is crucial for the regulation of many stem cells and when unregulated, can lead to cancer. My long-term goal is to understand how Notch signaling functions in vivo to control stem cells. My shorter-term goal has been to elucidate Notch signaling events in vivo from ligand-receptor activation to the transcriptional response that generates regulators of cell fate. To study Notch signaling in vivo, I use the nematode C. elegans where Notch signaling from a defined niche is essential for stem cell maintenance.
For more information, call 845-752-2309, or e-mail [email protected].
Time: 12:00 pm EST/GMT-5
Location: Reem-Kayden Center Laszlo Z. Bito '60 Auditorium