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Computational Modeling of Breast Cancer Microenvironmental Heterogeneity:An Agent-Based Approach
Tuesday, September 19, 2017

Breast tumor development is influenced by the individual properties of the tumor cells but also by other non-cancerous cells within its microenvironment. Based on experimental data, each tumor cell’s intrinsic properties are modeled, taking into account properties like cancer cell type and receptor numbers. In addition, we model the microenvironment’s influence on individual cancer cell properties, such as migration and proliferation. Then using agent-based modeling, we examine how individual cells interact with their microenvironment to form tumors and show how changes in that environment affect the tumor’s growth and invasion. From these results, we make predictions for potential therapies based on the interplay between the tumor and its microenvironment. 

Time: 12:00 pm
Location: Hegeman 204
Sponsor: Mathematics Program
Contact: Lauren Rose .
Phone: 845-758-7362

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