Chemistry and Biochemistry Program Presents

Reaction Progress Kinetic Analysis: A Powerful Methodology for Mechanistic Studies and Process Understanding

Reaction progress kinetic analysis streamlines pharmaceutical process development by exploiting the extensive data sets available from accurate in-situ monitoring of global reaction progress under practical operating conditions. This methodology involves the graphical manipulation of a critical minimum set of carefully designed experiments that permits rapid extraction of key information about the reaction’s driving forces and its robustness. While classical kinetic analysis can provide concentration dependences, RPKA provides the only in-situ method readily available for probing catalyst deactivation. Professor Donna Blackmond will speak about her research on the RPKA process and its advantages, as well as how studies of RPKA may help inform the direction of further reaction optimization.
 

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Professor Donna Blackmond is the John C. Martin Department Chair of the Department of Chemistry at Scripps Research. She is an elected member of both the National Academy of Sciences and the National Academy of Engineering, and has received the Chemical Pioneer Award from the American Institute of Chemists. Professor Blackmond was honored with the 2023 James Flack Norris Award in Physical Organic Chemistry “for fundamental investigations of complex organic reaction mechanisms in practical organic synthesis and breakthrough studies of the emergence of biological homochirality.”

Supported by the Jean Dreyfus Lectureship for Undergraduate Institutions Award
 

For more information, call 845-758-6822, or e-mail [email protected].

Time: 12:00 pm EDT/GMT-4

Location: Reem-Kayden Center Laszlo Z. Bito '60 Auditorium

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