Dean of the College Presents
Nutritional Control of C. elegans Germline Stem Cells
Thursday, December 3, 2015
Reem-Kayden Center Laszlo Z. Bito '60 Auditorium
12:00 pm EST/GMT-5
12:00 pm EST/GMT-5
Hannah Seidel, University of Wisconsin-Madison
Cells within multi-cellular organisms must continually respond to changing and often unpredictable physiological demands. We have discovered that stem cells within the gonad of the roundworm C. elegans stop dividing and become quiescent under starved conditions. This quiescence maintains the stem cell state even in absence of the conserved signaling pathway (Notch signaling) essential for stem cell maintenance under conditions of active proliferation. This work establishes C. elegans as a model for facultative stem cell quiescence and answers long-standing questions in the field of stem cell biology regarding the role of quiescence in maintaining the stem cell state.
For more information, call 845-752-2309, or e-mail [email protected].
Time: 12:00 pm EST/GMT-5
Location: Reem-Kayden Center Laszlo Z. Bito '60 Auditorium