Biology Program Presents
Using the Force with Amyloids for Good and Evil:
Ale, Biofilms, Commensalism, and Disease
Thursday, September 15, 2016
Reem-Kayden Center Laszlo Z. Bito '60 Auditorium
12:00 pm EDT/GMT-4
12:00 pm EDT/GMT-4
Peter Lipke
City University of New York, Brooklyn College
Amyloid protein aggregates are a stable form of proteins that occur frequently in nature, and they are infamous as markers of Alzheimer’s disease and other neurodegenerative disorders. In fungi, cell adhesion proteins can naturally form amyloid surface “nanodomains” in response to small forces such as that from flowing liquid or vortex mixing. These nanodomains cause very strong adhesion, allowing biofilms to resist disruption by force or antifungals. The biofilms in turn: help in fermentation (GOOD!), and confound antimicrobial therapies (EVIL!). Amyloid nanodomains also profoundly affect the way that host animals react to fungal infection by the commensal/opportunistic pathogen Candida albicans.City University of New York, Brooklyn College
For more information, call 845-752-2333, or e-mail [email protected].
Time: 12:00 pm EDT/GMT-4
Location: Reem-Kayden Center Laszlo Z. Bito '60 Auditorium