Dean of the College and Computer Science Program Present
From the Game of Life to Cancer Therapeutics:
My Journey in the World of Agent-based Computational Modeling
Monday, November 19, 2018
RKC 115
4:45 pm – 6:00 pm EST/GMT-5
4:45 pm – 6:00 pm EST/GMT-5
Kerri-Ann Norton, Computer Science Program, '04
Tissues are complex cellular systems that are maintained by cell-specific fate decisions determined by cell signaling and the stromal environment. Cancer occurs when there is a dis-regulation of these decisions due to influences from their intrinsic genetics or epigenetics but also due to changes in their surrounding environment. Agent-based modeling is a useful method for investigating the complex interactions between tumor and host environment, and the emergent behavior of the system under various parameter conditions. Dr. Norton’s research examines the interplay between cancer cells and the surrounding host environment, including intra-ductal pressure, blood vessels, therapeutics, macrophages, and fibroblasts. Agent-based modeling can provide insights into which specific targets or which specific therapeutic doses would be most effective at eliminating the tumor over a range of conditions that might not be cost effective to test in vivo. Dr. Norton’s talk will look at the various types of models used in her work over the years, beginning with her senior project at Bard College. The talk is designed to be accessible to undergraduate students.For more information, call 845-752-2359, or e-mail [email protected].
Time: 4:45 pm – 6:00 pm EST/GMT-5
Location: RKC 115